There are currently understood to be two primary cannabinoid receptors, but the debate continues on other potential receptors that may also be influenced by cannabinoid stimulation. CB1 receptors reside primarily in the nervous system and brain, and they relate to psychological processing and mental functions, such as emotions, memories, movement, pain, thinking, mood, and appetite. CB2 receptors exist in the major systems of the body and immune system, relating to functions in the organs, gut, heart, kidneys, and lymph cells of the body. Another known receptor found in the human body is the TRPV1 receptors, which reside in the skin. As the TRPV1 receptors collect cannabinoid molecules they help regulate itching sensations, heat, inflammation and can even help eczema and psoriasis.
While THC interacts directly with the CB1 receptors, CBD does not directly bind to the CB1 or CB2 receptors. Instead, it suppresses the enzyme that is responsible for breaking down Anandamine, a natural occurring cannabinoid found in the body. This cannabinoid is responsible for activating the CB1 and CB2 receptors, which triggers the body’s natural protective endocannabinoid response.
This natural response is triggered when the body senses something out of the ordinary, or anything that brings the body out of homeostasis. Think of homeostasis as the body running at optimal efficiency; the systems are working as they should and the hormone levels in the body are balanced appropriately. When something offsets this balance, the immune system and other systems of the body react to put the body back in harmony.
CBD products show tremendous promise as supplements for various conditions, allowing many people to avoid pharmaceuticals for their ailments, especially because many patients are now seeking more natural alternatives. The 2018 Farm Bill officially legalized the cultivation of industrial hemp, paving the way for CBD products to become a more mainstream treatment option for various conditions.
We look forward to educating others about this industry as it evolves at a record pace. If you have absolutely any questions or concerns about our products or about CBD in general, please feel free to contact us.
– Mango Jane